2022 NFL Playoffs: Arizona Cardinals vs. Los Angeles Rams NFC Wild Card Betting Odds, Preview, and Picks

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The Arizona Cardinals and the Los Angeles Rams are meeting again this season. After splitting their two games against each other back in the regular season, they will have their grudge match in the all-important Wild Card game this coming Monday in Tinseltown. Which team will advance to the next round?

Read on for our odds and preview for the Arizona Cardinals vs. Los Angeles Rams NFC Wild Card matchup below. And to be on top of all the developments from the 2022 NFL Playoffs and beyond, head on over to Nitrogen Sports Blog after this.

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2022 NFL Playoffs: Arizona Cardinals vs. Los Angeles Rams NFC Wild Card preview and odds 

Where: SoFi Stadium, Inglewood, California

When: Monday, January 17, 2022, 8:15 PM ET

Odds: Arizona Cardinals (+4) at Los Angeles Rams (-4); total: 44.0

Where to Watch: ABC/ESPN

What to know about the Arizona Cardinals

Arizona Cardinals vs. Los Angeles Rams betting odds for Arizona: +4

The Cardinals have had a bad form towards the end of the regular season, as they lost four of their past five games. To close out their regular-season schedule, the Cards suffered a 38-30 upset loss in Glendale to the Seattle Seahawks. Arizona is fortunate that it had a terrific first half in which they won seven stragiht to start the season. 

The Cards fell off in the final 11 weeks, as injuries took a toll on the team. Speaking of which, Arizona won’t have its best offensive weapon for the NFC Wild Card matchup against the Rams, with wide receiver DeAndre Hopkins still on the injured reserve. 

Meanwhile, running back James Conner is considered questionable for the Rams game and his availability could be decided on the day on Monday, so that’s one thing to keep an eye close on. Conner rushed for two touchdowns in the Cardinals’ 37-20 win in LA over the Rams back in Week 4, while Kyler Murray completed 24-of-32 passes for 268 yards and a pair of touchdowns.

What to know about the Los Angeles Rams

Arizona Cardinals vs. Los Angeles Rams betting odds for LA: -4

The Rams also lost their final assignment of the regular season, as they got thwarted by the San Francisco 49ers in a 27-24 overtime loss at home. Still, the Rams had a pretty strong conclusion to the regular season, winning all but one of their six games after Week 12. They also avenged their loss to the Cardinals earlier this season with a 30-23 victory in Glendale in Week 14. 

The Rams made sure to keep Murray grounded that time around, as the Cardinals quarterback passed for 383 yards but had zero touchdowns and got picked twice all the while Matthew Stafford was throwing darts on the other end of the field. Stafford went 23-of-30 for 287 passing yards and three touchdowns in that game. 

Given the slump of the Cardinals, Stafford and the Rams’ passing game could spell even more trouble for Arizona. Cooper Kupp is almost a lock to wreak havoc downfield against any team, having burned opposing secondaries in the entire regular season. 



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Arizona Cardinals vs. Los Angeles Rams betting trends

  • The Cardinals are 5-0 ATS in their last five games after giving up over 150 rushing yards in the last game. They allowed 202 rushing yards to Seattle in Week 18.
  • The Rams are 28-13-1 ATS in their last 42 games versus NFC teams.

Where to make Arizona Cardinals vs. Los Angeles Rams picks

Arizona Cardinals vs. Los Angeles Rams odds are available at Nitrogen Sports. Create a free Nitrogen Sports account to start placing stakes on all the smash-mouth action from the NFL gridiron right now. 

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What’s your Arizona Cardinals vs. Los Angeles Rams NFC Wild Card prediction?

This game could be a toss-up. Both teams are capable of playing like true Super Bowl favorites but have also frustrated their respective fanbases with letdown performances in the regular season. However, it’s the Rams who are in a much better form based on recent performance and also have the advantage of playing at home. Then again, the Cards have defeated LA at SoFi Stadium earlier this season. This matchup could be decided in the final drive of the contedst.

Be sure to read our NFL betting guide to get you ready for the 2022 NFL Playoffs’ wagering action. To keep up on the latest NFL offseason news, make sure to head on to our NFL Hub here on the blog.

*All stated odds are subject to change without prior notice.

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